U.S. National Security Advisor Susan Rice '86 will give a special public lecture at the Freeman Spogli Institute on Climate Change and National Security.

Doors open at 4:00pm. Space is limited.

 

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Most Americans will get at least one faulty diagnosis in their lifetime, sometimes with devastating consequences. “Urgent change is warranted to address this challenge,” according to a recent landmark report from the Institute of Medicine.

The September report, by a committee of medical experts, found that despite dramatic improvements in patient safety over the last 15 years, diagnostic errors have been the critical blind spot of health-care providers.

Kathryn McDonald, executive director of Stanford’s Center for Health Policy/Center for Primary Care and Outcomes Research, is a member of the committee that wrote the report, “Improving Diagnosis in Health Care.”

We ask McDonald Five Questions about the report’s findings and also got her suggestions for limiting one of the most overlooked health-care dilemmas today. You can read her responses here on the Stanford Medicine news center website.

Read more here about the report when it came out last month.

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Basic science aims to advance knowledge, not only develop new drugs or cure disease. Yet today's biomedical innovations are only possible because of fundamental research conducted decades ago. As national funding priorities shift toward applied research, young basic scientists face the most challenging funding landscape in 50 years, diverting many of them to new careers altogether. Though impossible to divine where the experiments of Stanford investigators and researchers will lead them, investing in their work — and in basic science in general — is crucial to keeping the next great discovery alive.

In this multimedia photo essay, Magnum photographer Peter van Agtmael and FSI digital media associate Kylie Gordon, shine light on the interdisciplinary medical and scientific research being conducted at Stanford — which could lead to the #NextGreatDiscovery.

 

 

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At her lab bench, postdoctoral fellow Pascale Guiton sets up a polymerase chain reaction to generate copies of Toxoplasma gondii DNA. T. gondii is one of the most common parasites, with an estimated one third of the global population infected.
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The Program on American Democracy in Comparative Perspective is holding a conference on Democracy and its Discontents on October 8-10 in Budapest, Hungary. The conference, co-hosted with Central European University, will bring together scholars of American and European politics to examine topics such as democratic backsliding, inequality, and money in politics. Saskia Sassen of Columbia University will deliver the keynote address. 

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In a recent piece in Stanford News, FSI Senior Fellow Larry Diamond expresses his thoughts on the ebbing of global democratic expansion, highlighting that not all countries have equal opportunities at achieving democracy and that democratic change should be approached multilaterally.

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Larry Diamond speaks on his new book "In Search of Democracy," at the National Endowment for Democracy (NED) in Washington, D.C.
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Most Americans will get at least one faulty diagnosis in their lifetime, sometimes with devastating consequences and “urgent change is warranted to address this challenge,” a panel of medical experts said Tuesday.

In a landmark report by the Institute of Medicine, the medical arm of the National Academies of Sciences, Engineering and Medicine, the experts said that despite dramatic improvements in patient safety over the last 15 years, diagnostic errors have been the critical blind spot of health-care providers.

Exact figures on diagnostic errors are hard to come by, as reporting is not required. Some medical experts have estimated that more than 12 million adults are misdiagnosed every year.

“Despite the pervasiveness of diagnostic error and the risk for patient harm, they have been largely unappreciated within the quality-safety movement in healthcare — and this cannot and must not continue,” said Dr. Victor Dzau, president of the Institute of Medicine, an independent organization of the country’s leading medical and health policy researchers.

“Diagnostic errors are a significant contributor to patient harm and have received too little attention until now,” he said at a public briefing in Washington, D.C., about the report, “Improving Diagnosis in Health Care.”

To address the challenge, the IOM convened the committee comprised of medical and health policy researchers to improve diagnosis in medicine. The Committee on Diagnostic Error in Health Care members include experts from Stanford, Harvard, Drexel, Tufts, the Memorial-Sloan Kettering Cancer Center, Kaiser Permanente and more than a dozen other universities and national medical organizations.

“We defined diagnostic error from a patient's perspective, and brought together the research so far that clearly shows the opportunity and grave need to improve the current situation,” said Kathryn M. McDonald executive director of Stanford’s Center for Health Policy/Center for Primary Care and Outcomes Research, and a member of the IOM committee.

“The report is packed with reasons and directions for action from all, in ways that support what patients deserve from the health-care system: freedom from worry about inattention to diagnostic errors,” McDonald said. “That's been the status quo for too long.”

The committee issued a set of goals to reduce diagnostic errors and improve medical outcomes. They recommend that the health-care community:

  1. Facilitate more effective teamwork in the diagnostic process among health-care professionals, patients and their families.

  2. Enhance health-care professional education and training in the diagnostic process.

  3. Ensure that health information technologies support patients and health-care professionals in the diagnostic process.

  4. Develop and deploy approaches to identify, learn from and reduce diagnostic errors and near misses in clinical practice.

  5. Establish a work system and culture that supports the diagnostic process and improvements in diagnostic performances.

  6. Develop a reporting environment and medical liability system that facilitates improved diagnosis through learning from diagnostic errors and near misses.

  7. Design a payment and care delivery environment that supports the diagnostic process.

  8. And provide dedicated funding for research on the diagnostic process and diagnostic errors.

The experts emphasized that medical education must include more of an emphasis on the diagnostic process. And new technologies, such as electronic health records, should be built on better collaboration among the IT vendors, users and the Office of the National Coordinator for Health Information Technology.

The new study was an extension of two benchmark reports by the institute released 15 years ago, which revealed the startling statistic that 100,000 Americans die in hospitals every year due to medical errors.

“These landmark reports from IOM reverberated throughout the healthcare community and were the impetus for system-wide improvement in patient safety and quality,” Dzau said.

The Department of Health and Human Services reported in December that there was a decline from 2010 to 2013 in hospital-acquired infections, which translated to 1.3 million patients and $12 billion in health spending avoided.

“You can see we have come a long way,” Dzau said. But, he added: “The critical element that has been absent from patient safety and quality is diagnostic error.”

In a video released at the public briefing, two patients talk about their own misdiagnosis and that of a loved one, and how those errors forever changed their lives. They were told they were overreacting and not to question their doctor. One said she was embarrassed at having wasted the valuable time of the hospital doctors and nurses.

“The video has two patients for whom things went poorly and one who had a first-class diagnostic experience because of excellent teamwork,” McDonald said. “And this is one of the key messages of the report. We need less of the old model of diagnosis from one expert to more of a teamwork approach to the diagnostic process.”

Dr. John Ball, chair of the committee and executive vice president emeritus of the American College of Physicians, said clinicians must work toward a culture where patients are central to the solution.

“Patients and families are first; diagnostics are second and those who support it, third,” said Ball. “This is an issue that matters to patients, and we’re shining a light on it.”

Ball said getting the right diagnosis is critical because it impacts every other health care decision that follows, as well as the quality of life for the patient.

The committee members were asked during the briefing why they were not recommending that misdiagnosis reporting be mandatory, something that likely will lead to controversy.

“The committee believes that given the lack of agreement on what constitutes a diagnostic error, given the complexity of hard data and the lack of valid measurement approaches, the time was not right to call for mandatory reporting,” Ball said. “Instead it was appropriate at this time to leverage the intrinsic motivation of health-care professionals to improve the diagnostic performance and to treat diagnostic error in the same way we treat other quality improvement efforts by health-care organizations.”

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The three women who are the first doctoral candidates in the School of Medicine’s new PhD in Health Policy program have one guiding belief:  economics, decision science and data are now key to improving health care.

Stanford Health Policy, through the Department of Health Research and Policy at the School of Medicine, launched the PhD program to educate the next generation of scholarly leaders in the field of health policy.

And the first crop of candidates is taking their backgrounds in science and economics to pursue health policy careers based on medical information technology, data and analytics.

“We live in an era where information in health care is more rapidly and readily available than ever before,” said Catherine Lei, who will focus on the industrial organization of health care, the effects of insurance costs and the impact of regulation on health insurance markets.

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“The burgeoning ‘big data’ revolution is beginning to collectively help researchers tackle long-standing issues of health care spread and quality, determinants of health, and how policies could best improve health,” said the recent Princeton University graduate who majored in economics and finance.

“Whether it be the digitization of medical records, the aggregation of pharmaceutical companies’ research into electronic databases, or the increased transparency of the health-care sector as a whole — stakeholders from every corner of the industry recognize that this is a critical turning point in health care,” said Lei.

Kyu Eun Lee, who worked as a research assistant at the Harvard Center for Health Decision Science before joining Stanford, intends to develop mathematical models for health interventions in Asia and other parts of the developing world.

“I am seeking advanced training in quantitative methodology and the application of those skills to support decision-making in a global health context,” said Lee, who graduated from Pohang University of Science and Technology in South Korea and then got her master’s of science at the University of Minnesota.

“I am particularly interested in model-based, cost-effectiveness analysis of cancer interventions in South or Southeast Asia, where the risks of communicable and noncommunicable diseases compete under limited resources,” she said.

The new program offers coursework in two tracks: Health Economics, including the economic behavior of individuals, providers, insurers and governments and how their actions affect health and medical care; and Decision Sciences, which uses quantitative techniques to assess the effectiveness and value of medical treatments.

“The new PhD program really developed because of our aim to offer premier educational programs that will train the next generation of health policy leaders,” said Laurence Baker, professor of Health Research and Policy and chief of Health Services Research in the department of Health Research and Policy.

“One of the real strengths of the program is its context at Stanford, with a rich set of opportunities for health policy students to interact with the clinicians and scientists from around the school of medicine and the university,” said Baker, who is also an affiliated faculty member at the Center for Health Policy/Center for Primary Care and Outcomes Research (CHP/PCOR).

Yiqun Chen, who will focus on the supply and demand of health care both in the United States and China, said her double major in economics and medicine at Peking University made her aware of the integral role that economics plays in providing an analytic framework for studying the meaty issues in health care today.Chen, who went on to get her master’s in economics at Duke University, has published several papers and intends to investigate whether Medicaid payment increases to nursing homes result in cost offsets.

“The utilization of hospital services is high among nursing home residents; yet a large proportion of stays are documented to be avoidable through provision of better quality of nursing home care,” Chen said.

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She will also research the recent consolidation of health insurers and of health care providers and how that is impacting the consumer.

“As a result of such consolidation, not only is there a potential loss of consumer choice, but it gives the pricing power to insurers and health-care service suppliers,” Chen said. And those who argue health-care and insurance consolidation results in greater efficiencies have yet to document these gains or losses — something she intends to do.

Faculty belonging to the health policy centers will advise the PhD candidates. The students will take courses in health economics, health insurance and government program operations, health financing, international health policy and economic development, as well as the cost-effectiveness analysis of new medical technologies.

“The PhD program enables us to train clinicians and non-clinicians in state-of-the-art methods of health policy analysis,” said Douglas K. Owens, director of CHP/PCOR within the Freeman Spogli Institute of International Studies.

Coursework in the new program will also cover relevant statistical and methodological approaches to public health concerns such as obesity and chronic disease.

"Our PhD students will learn from faculty across the University who bring perspectives from economics, medicine, law, decision science, business and other disciplines," said Michelle Mello, a professor of law and professor of health research and policy at the School of Medicine. "They will become truly cross-disciplinary thinkers and problem solvers."

Learn more here. 

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Maria Polyakova, PhD, is Associate Professor of Health Policy at Stanford School of Medicine and Associate Professor (by courtesy) in the Department of Economics at Stanford University, where she is also a Senior Fellow at the Stanford Institute for Economic Policy Research (SIEPR). She is a Research Associate at the National Bureau of Economic Research (NBER) and serves as an Editor of the Journal of Health Economics. Her research spans many areas of health economics, including health insurance, healthcare labor markets, and individual decision-making in health and healthcare. A unifying thread is evaluating whether markets and government policy effectively serve individuals and families or introduce distortions. Her ongoing work focuses on how families navigate prolonged health shocks. Maria received her BA in Economics & Mathematics and German Studies (with a concentration in History) from Yale University in 2008 and her PhD in Economics from MIT in 2014.

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In an op-ed for The New York TimesLarry Diamond presents a timeline of democracy charting the spread, regression, and sometimes even collapse, of democracy in the last 40 years.

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Anti-government protesters wave national flags during a demonstration in Bangkok on November 25, 2013.
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