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Despite predictions of their eradication in the 1960s, infectious diseases remain a significant cause of global health, economic, and social problems. There has been a renewed focus on the background "matrix" of infections that occur around the globe, as well as on emerging, re-emerging, and deliberately emerging (i.e. bioterror) agents. This talk will provide a global health perspective on infectious diseases in 2007, and highlight the lessons that can be learned from three conditions (HIV/AIDS, influenza, and SARS).

Daniel Libraty is an associate professor of medicine at the University of Massachusetts Medical School. He is a member of the Center for Infectious Disease and Vaccine Research (CIDVR), and the Division of Infectious Diseases/Department of Medicine. He received his MD degree from the University of California, San Diego. He completed his post-graduate residency in internal medicine at the University of California, San Francisco, and obtained subspecialty training in infectious diseases at the University of California, Los Angeles. His research focuses on understanding the protective and pathogenic human immune responses to emerging and re-emerging viral diseases such as dengue, hantavirus, SARS, and influenza. He has lived and traveled extensively throughout Southeast Asia and other parts of the world in the course of working on these infectious diseases.

Reuben W. Hills Conference Room

Daniel Libraty Associate Professor, Department of Medicine Speaker University of Massachusetts
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Executive Director of UNAIDS since its creation in 1995 and Under Secretary-General of the United Nations, Dr. Peter Piot comes from a distinguished academic and scientific career focusing on AIDS and women's health in the developing world.

Drawing on his skills as a scientist, manager, and activist, Dr. Piot has challenged world leaders to view AIDS in the context of social and economic development as well as security.

Under his leadership, UNAIDS has become the chief advocate of worldwide action against AIDS. It has brought together ten organizations of the United Nations system around a common agenda on AIDS, spearheading UN reform.

Dr. Piot earned a medical degree from the University of Ghent, a PhD in Microbiology from the University of Antwerp, Belgium and was a Senior Fellow at the University of Washington in Seattle. After graduating from medical school, Dr. Piot co-discovered the Ebola virus in Zaire in 1976.

In the 1980s, Dr. Piot launched and expanded a series of collaborative projects in Burundi, Côte d'Ivoire, Kenya, Tanzania, and Zaire. Projet SIDA (Project AIDS) in Kinshasa, Zaire, was the first international project on AIDS in Africa and is widely acknowledged as having provided the foundations of our understanding of HIV infection in Africa. He was a professor of microbiology, and of public health at the Institute of Tropical Medicine, in Antwerp, and the Universities of Nairobi, Brussels, and Lausanne.

In 1992, Dr. Piot joined the Global Programme on AIDS of the World Health Organization, in Geneva, as Associate Director.

Born in 1949 in Belgium, Dr. Piot is fluent in three languages and is the author of 16 books and more than 500 scientific articles. He has received numerous awards for scientific and societal achievement, and was made a Baron by King Albert II of Belgium in 1995. He is a member of the Institute of Medicine of the National Academy of Sciences of the United States and the Royal Academy of Medicine of Belgium, and is a Fellow of the Royal College of Physicians of London, UK.

For more information about Dr. Piot, read "The Life of a Virus Hunter" from Newsweek's special edition of May 15, 2006, AIDS at 25.

Kresge Auditorium

Dr. Peter Piot Executive Director, UNAIDS and Under Secretary-General, United Nations Speaker
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We have learned little from the cataclysms of September 11 and Hurricane Katrina. When it comes to catastrophe, America is living on borrowed time--and squandering it.

The truth is, acts of terror cannot always be prevented, and nature continues to show its fury in frighteningly unpredictable ways. Resiliency, argues Flynn, must now become our national motto. With chilling frankness and clarity, Flynn paints an all-too-real scenario of the threats we face within our own borders. A terrorist attack on a tanker carrying liquefied natural gas into Boston Harbor could kill thousands and leave millions more of New Englanders without power or heat. The destruction of a ship with a cargo of oil in Long Beach, California, could bring the West Coast economy to its knees and endanger the surrounding population. But even these alarmingly plausible terrorist scenarios pale in comparison to the potential destruction wrought by a major earthquake or hurricane.

Our growing exposure to man-made and natural perils is largely rooted in our own negligence, as we take for granted the infrastructure handed down to us by earlier generations. Once the envy of the world, this infrastructure is now crumbling. After decades of neglect, our public health system leaves us at the mercy of microbes that could kill millions in the next flu pandemic. Flash flooding could wipe out a fifty-year-old dam north of Phoenix, placing thousands of homes and lives at risk. The next San Francisco earthquake could destroy century-old levees, contaminating the freshwater supply that most of California relies on for survival.

It doesn't have to be this way. The Edge of Disaster tells us what we can do about it, as individuals and as a society. We can--and, Flynn argues, we must--construct a more resilient nation. With the wounds of recent national tragedies still unhealed, the time to act is now. By tackling head-on, eyes open the perils that lie before us, we can remain true to our most important and endearing national trait: our sense of optimism about the future and our conviction that we can change it for the better for ourselves--and our children.

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Books
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Council on Foreign Relations and Random House
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This project involves political scientists, economists, and medical researchers to address the question of whether hunger, poverty, disease and agricultural resource constraints foster civil conflict and international terrorism. Economists have elucidated the links between agricultural stagnation, poverty, and food insecurity, and political scientists have empirically analyzed the role of poverty in facilitating civil conflict.

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The speaker will describe his experiences over ten years of developing a comprehensive program to engage the formerly top secret Soviet biological weapons complex through joint scientific research and disease surveillance. He will also discuss how lessons learned can be applied to potential new efforts to reduce global threats of bioterrorism and potential pandemics.

Andrew Weber is the adviser for cooperative threat reduction policy in the Office of the Secretary of Defense. His responsibilities include developing and overseeing CTR biological threat reduction programs in the former Soviet Union, and nuclear and chemical weapons threat reduction projects in Central Asia. Before coming to the Office of the Secretary of Defense in 1996, Weber served as a U.S. Foreign Service officer in Saudi Arabia, Germany, Kazakhstan, and Hong Kong. Weber holds an MSFS degree from Georgetown University and a BA from Cornell University. He speaks Russian. Weber is an adjunct professor at the Georgetown University Graduate School of Foreign Service.

Reuben W. Hills Conference Room

Andrew Weber Senior Adviser for Cooperative Threat Reduction Policy Speaker Office of the Secretary of Defense
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The article asserts that globalization has made the world a more dangerous and less orderly place. The authors argue that since the emergence and expansion of globalization in the 1990s, the world has experienced more problems such as increasing terrorist activity, widening gaps between religious and cultural ideologies, unstable global financial systems, expanding dangers of pandemic disease, and the growing threat of global climate change.

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Journal Articles
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Foreign Policy
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The use of chemical fertilizers in developing countries made possible the Green Revolution, and as a result many regions once visited by periodic famines are now food self-sufficient. However, there is a growing recognition that the injudicious use of chemical fertilizers may have adverse environmental consequences including toxic algal blooms and damage to productive ocean fisheries.

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"Pandemic influenza is probably the world's most serious near-term public health threat," CISAC's Lawrence M. Wein points out, yet the nation is unprepared to treat the ill if a strain similar to that of the 1918 Spanish flu breaks out. A relatively inexpensive way to keep the illness from spreading may be within reach, though. In this New York Times op-ed, Wein explains how stockpiles of inexpensive masks and respirators could provide critical protection if a deadly flu virus hits.
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